Unable to connect to database - 10:59:51 Unable to connect to database - 10:59:52 SQL Statement is null or not a SELECT - 10:59:52 SQL Statement is null or not a DELETE - 10:59:52 Botany & Plant Biology 2007 - Abstract Search
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Abstract Detail

Manipulation of Host Signaling by Pathogens

He, Sheng-Yang [1].

Bacterial virulence factors: Excellent molecular probes of plant cellular functions.

Plants have evolved a powerful and multi-layered immune system to defend against infection by most microbial organisms. However, successful pathogens, such as Pseudomonas syringae pv. tomato (Pst) strain DC3000, have developed specific virulence factors to overcome host immunity and cause diseases. During infection, Pst DC3000 produces several virulence factors to engage multiple host cell types and diverse host physical and chemical barriers. The phytotoxin coronatine, a possible mimic of the plant hormone jasmonate, contributes to bacterial invasion through stomata, development of disease symptoms, and virulence in local and systemic tissues. The bacterial type III secretion system (TTSS) enables the extracellularly localized Pst DC3000 to deliver a battery of virulence “effectors” directly into the host cell. The action of these effectors is associated with suppression of host defense, development of disease symptoms (necrosis and chlorosis) and, presumably, release of nutrients from host cells. Study of the molecular action of effector proteins and coronatine is revealing a fascinating array of host cellular functions associated with vesicle traffic, stomatal function, jasmonate signaling, cell wall dynamics, and senescence-associated leaf chlorosis.

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1 - Michigan State University, DOE Plant Research Laboratory, 222 Plant Biology Bldg., Michigan State University, East Lansing, MI, 48824, USA

protein traffic
host immunity
jasmonate signaling
salicylic acid
cell wall.

Presentation Type: ASPB Major Symposium
Session: S05
Location: International Ballroom/Hilton
Date: Tuesday, July 10th, 2007
Time: 9:15 AM
Number: S05002
Abstract ID:971

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