Plant Photoreceptors and Photomorphogenesis
Lin, Chentao .
How Cryptochromes work, a case study in Arabidopsis.
Cryptochromes are blue/UV-A light receptors found in bacterial, plants, and animals. Arabidopsis genome encodes two cryptochromes, CRY1 and CRY2, which mediate blue light inhibition of hypocotyl elongation and long-day promotion of floral initiation, respectively. Cryptochromes are believed to regulate development by affecting gene expression, but how cryptochromes regulate changes of gene expression in response to light is unclear. Over hundreds of cryptochrome-regulated genes have been identified using array-profiling, but the functional relevance of few of those genes has been tested and the mode of cryptochrome-regulated gene expression is also unknown. Prompted by a result of a genetic study of suppressors of the cry1cry2 mutant, we systematically investigate the role of GA metabolism/catabolism genes in photomorphogenesis. We showed that cryptochromes positively regulate mRNA expression of GA2ox genes but negatively regulate GA20ox and GA3ox genes. These results are consistent with a hypothesis that cryptochromes may regulate GA metabolic/catabolic genes to regulate hypocotyl elongation response. To further investigate how cryptochromes regulate gene expression, we studied CRY2-interacting proteins. Results of this study will be discussed.
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1 - University of California, Los Angeles, Molecular, Cell and Developmental Biology
Cryptochrome 1 and 2
CRY1 and 2
Presentation Type: Symposium or Colloquium Presentation
Location: Boulevard C/Hilton
Date: Monday, July 9th, 2007
Time: 9:00 AM