Abstract Detail
Mechanisms of Gene Regulation Gilding, Edward [1], Marks, M. David [2]. An Arabidopsis MYB is required for the coordination of developmental events during trichome morphogenesis. Incipient Arabidopsis trichomes assume the trichome cell fate through a pathway that relies upon the dosage of a suite of transcriptional regulators. This suite includes two classes of proteins that have an expanded lineage in plants, the R2R3 and R3 MYB proteins. While R2R3 and R3 MYB proteins act as positive and negative regulators of the trichome cell fate respectively, an R2R3 MYB protein has been found that functions at a later period during trichome development and is not a part of the suite of early regulators. Insertional mutations in AtMYB106 (At3G01140) produces trichomes with extra branches, and is described here under the name MOOSE (MOO). These trichomes continue to form branches late in trichome development indicating that MOO is both a negative regulator of trichome branch formation and a developmental coordinator during several stages of trichome growth. Morphometric analysis of moo and another extra branched mutation in the the R3 MYB triptychon (try), indicates that both mutations cause the formation of similarly sized and proportioned trichomes. The predicted MOO protein does not have the motifs required to interact with two other members of the trichome cell fate regulatory suite as try does. The exact mechanism by which the loss of MOO function results in extra branched trichomes is the focus of future work. Ultimately, this includes the discovery of target genes that are directly regulated by MOO. Log in to add this item to your schedule
1 - Univeristy of Minnesota, Department of Plant Biology, 250 Biological Sciences Center, 1445 Gortner Ave, St. Paul, MN, 55108, USA 2 - Univeristy of Minnesota, Department of Plant Biology
Keywords: transcriptional regulation gene regulation cell growth regulation MYB trichome.
Presentation Type: Plant Biology Abstract Session: P Location: Exhibit Hall (Northeast, Southwest & Southeast)/Hilton Date: Sunday, July 8th, 2007 Time: 8:00 AM Number: P36055 Abstract ID:2327 |