Plant Phylogenomics: Defining Synergies Between Plant Systematics and Genome Biology
Vision, Todd .
Known unknowns: Modeling gene content and gene order in the angiosperms.
A major goal of comparative genomics is to facilitate the characterization of relatively intractable genomes by leveraging genome data from model species. In particular, the promise of comparative mapping in plants has been that model organisms like Arabidopsis could be used to predict the gene content and order within the genomes of species that have been characterized only by relatively sparse gene-based maps. However, this is a challenge for distantly related plant species because of the prevalence of genome duplications, and subsequent massive gene loss, in the ancestors of so many contemporary plant species. We attempt to probabilistically predict the presence and absence of genes using a phylogeny of duplicated chromosomal segments from multiple angiosperm species. Now that genome sequences exist for several distinct lineages of angiosperms, how well can we predict gene content and order in unsequenced genomes, and what can we learn from this exercise about the processes of genome evolution?
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1 - University of North Carolina, Department of Biology, Cb#3280, Chapel Hill, North Carolina, 27599-3280, USA
Presentation Type: Symposium or Colloquium Presentation
Location: Stevens 2/Hilton
Date: Monday, July 9th, 2007
Time: 8:30 AM